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Article

IGHV mutational status and BCR stereotypy in chronic lymphocytic leukemia: A Turkish cohort analysis.

Annals of hematology - 3 Jun 2026

Yüksel Seher, Aygün Rahmi Şinasi, Yüksel Merve, Örüncü Mehmet Berk, Serbes Ezgi Dicle, Cengiz Seval Güldane, Arslan Önder, Özcan Muhit, Kuzu Işınsu

Abstract excerpt

Immunoglobulin heavy chain variable region (IGHV) mutational status and B-cell receptor (BCR) stereotypy are established prognostic markers in chronic lymphocytic leukemia (CLL). However, immunogenetic data from Türkiye and surrounding regions are scarce. We evaluated IGHV mutational status, BCR stereotypy including nearest subset assignment, and their clinical and cytogenetic correlates in a real-world Turkish...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Heavy Chains

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Share to In Situ Hybridization, Fluorescence

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Receptors, Antigen, B-Cell

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Source

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Identifiers

PMID: 42230397
DOI: 10.1007/s00277-026-07096-9
PMCID: PMC13447546

Genes

BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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