Article
Prognostic impact of prevalent chronic lymphocytic leukemia stereotyped subsets: analysis within prospective clinical trials of the German CLL Study Group (GCLLSG).
Haematologica - 1 Nov 2020
Jaramillo Sonia, Agathangelidis Andreas, Schneider Christof, Bahlo Jasmin, Robrecht Sandra, Tausch Eugen, Bloehdorn Johannes, Hoechstetter Manuela, Fischer Kirsten, Eichhorst Barbara, Goede Valentin, Hallek Michael, Döhner Hartmut, Rosenquist Richard, Ghia Paolo, Stamatopoulos Kostas, Stilgenbauer Stephan
Abstract excerpt
Almost one-third of all patients with chronic lymphocytic leukemia (CLL) express stereotyped B cell receptor immunoglobulins (BcR IG) and can be assigned to distinct subsets, each with a particular BcR IG. The largest stereotyped subsets are #1, #2, #4 and #8, associated with specific clinicobiological characteristics and outcomes in retrospective studies. We assessed the associations and prognostic value of...
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