Article
[Biological characteristics and clinical significance of stereotyped B-cell receptor in chronic lymphocytic leukemia].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 14 Feb 2024
Qiu T L, Li J Y, Xia Y
Abstract excerpt
Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western adults, although the incidence of CLL is relatively low in Asian populations. However, with the aging population, the incidence of CLL is increasing in China. The interaction between CLL cells and the microenvironment plays a crucial role in the recognition of antigens by the B-cell receptor immunoglobulin (BCR IG). The mutational...
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