Phenotype-specific immune profiles and outcomes in childhood autoimmune neutropenia: A 20-year cohort study.

doi:10.1111/bjh.70588

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Article

Phenotype-specific immune profiles and outcomes in childhood autoimmune neutropenia: A 20-year cohort study.

British journal of haematology - 1 Sept 2026

Saougou Ioanna, Kosmeri Chrysoula, Chaliasos Nikolaos, Mavroudi Irene, Pontikoglou Charalampos, Makis Alexandros

Abstract excerpt

Childhood autoimmune neutropenia (AIN) encompasses heterogeneous entities; phenotype-specific immunological profiles and their relationship to infection outcomes remain incompletely defined. To characterise clinical, immunological and long-term outcomes across distinct phenotypes of childhood AIN. We conducted a retrospective cohort study of 112 children with antibody-confirmed AIN at a tertiary centre over...

Read the complete abstract on PubMed

Topics

Humans
Neutropenia
Female
Autoimmune Diseases
Child
Male
Child, Preschool

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Phenotype

Retrospective Studies

Adolescent

Infant

Lymphocyte Subsets

Cohort Studies

Cytopenia

Source

Open in PubMed Open full text

Identifiers

PMID: 42227604
DOI: 10.1111/bjh.70588
PMCID: PMC13570138

Genes

CD19
CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

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