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Sport, genetic susceptibility, and the risk of benign prostatic hyperplasia: a large prospective cohort study.

World journal of urology - 1 Jun 2026

Zhao Zihao, Wu Changjing, Fu Shiliang, Cheng Chao, Xiong Yang, Yuan Jiuhong, Wang Xianding, Qin Feng

Abstract excerpt

PURPOSE: Benign prostatic hyperplasia (BPH) is a common age-related urological condition influenced by both modifiable lifestyle factors and genetic susceptibility. This large cohort study was performed to examine the association between physical activities and incident BPH, and assess modification by genetic susceptibility using a polygenic risk score (PRS). METHODS: We conducted a prospective cohort study of...

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PMID: 42223661
DOI: 10.1007/s00345-026-06505-y

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