Article
The causal effect of metabolic syndrome and its components on benign prostatic hyperplasia: A univariable and multivariable Mendelian randomization study.
The Prostate - 1 Oct 2023
Lv Kaikai, Yang Guorong, Wu Yangyang, Xia Xinze, Hao Xiaowei, Pang Aibo, Han Dong, Yuan Qing, Song Tao
Abstract excerpt
BACKGROUND: Previous observational studies have indicated that metabolic abnormalities are associated with benign prostatic hyperplasia (BPH). The limitations of the research methodology of observational studies do not allow causal inference to be drawn; however, Mendelian randomization (MR) can clarify this. METHODS: Using summary-level data from genome-wide association studies, we conducted a two-sample MR...
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