Cardiovascular disease risk factors in women with O-desmethylangolensin producing and non-producing gut microbial metabotypes: an observational study.

Abstract excerpt

BACKGROUND: Daidzein, an isoflavone in soy, is metabolized to O-desmethylangolensin (ODMA) by select gut bacteria. Not all individuals have gut microbiomes capable of producing ODMA, resulting in ODMA producer and non-producer metabotypes. A limited body of research suggests that ODMA producers have lower systolic blood pressure, percent body fat and total cholesterol, compared to non-producers. More work is...

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