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Article

CDC48A and the ubiquitin-associated domain protein PUX10 regulate the ubiquitin-dependent degradation of peroxisomal proteins in Arabidopsis.

The Plant cell - 2 Jun 2026

Li Jinge, Yu Shijiao, Zang Xiaoxiao, Wang Shuo, Qin Zhaoxia, Ma Changle

Abstract excerpt

Homeostasis of peroxisomes and their constituents maintains peroxisome function during plant growth, development, and environmental responses. Protein degradation maintains peroxisome homeostasis by eliminating misfolded or damaged proteins and precisely regulating the abundance of specific proteins. However, the mechanism by which a subset of peroxisomal proteins is transported from the peroxisome to the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42203491
DOI: 10.1093/plcell/koag149

Genes

PEX5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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CDC48A and the ubiquitin-associated domain protein PUX10 regulate the ubiquitin-dependent degradation of peroxisomal proteins in Arabidopsis.PMID 42203491Read ↗

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Disrupting autophagy restores peroxisome function to an Arabidopsis lon2 mutant and reveals a role for the LON2 protease in peroxisomal matrix protein degradation.Semantic proximity Read ↗

The PEX1 ATPase Stabilizes PEX6 and Plays Essential Roles in Peroxisome Biology.Semantic proximity Read ↗

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Protein domain-domain interactions and requirements for the negative regulation of Arabidopsis CDC48/p97 by the plant ubiquitin regulatory X (UBX) domain-containing protein, PUX1.Semantic proximity Read ↗

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