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Development and validation of PCR-RFLP assays for genotyping PRNP and PRND polymorphisms in New Zealand rabbits in Vietnam.

Research in veterinary science - 1 Sept 2026

Bui Anh Phu Nam, Thong Le Quang, Duong Cuong Ngoc, Van Quang Ta, Giao Nguyen Dang My

Abstract excerpt

Genetic variation within the prion gene cluster (PRNP-PRND) has been proposed as a contributing factor to the prion-disease biology of rabbits, motivating the development of scalable genotyping tools for population screening and downstream genotype-phenotype studies. Here, we developed and validated PCR-restriction fragment length polymorphism (PCR-RFLP) assays to genotype one PRNP variant (c.234C > T) and two...

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Identifiers

PMID: 42202633
DOI: 10.1016/j.rvsc.2026.106215

Genes

PRND
PRNP
GC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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