Article
Sickle Cell Disease: Can genetic variability influence pregnancy outcomes?
Blood cells, molecules & diseases - 1 Jul 2026
Ginete Catarina, Cruz Carolina, Delgadinho Mariana, Mendes Manuela, Simão Fernanda, Alves Lígia, Vasconcelos Jocelyne, Borralho Paula, Brito Miguel
Abstract excerpt
Pregnancy in Sickle Cell Disease (SCD), a severe hereditary genetic condition, highly prevalent in Sub-Saharan African countries, is associated with increased risk of complications and severe outcomes in pregnancy, like intrauterine growth restriction, low birth weight, premature birth, miscarriage, stillbirth, pre-eclampsia, and maternal mortality. Several factors have been identified as associated with the...
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