Emerging Trends in HIV-1 Sub-Subtype A6 in Belgium: Transmission Dynamics, Drug Resistance, and Subtyping Tool Evaluation.

doi:10.3390/v18050554

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Emerging Trends in HIV-1 Sub-Subtype A6 in Belgium: Transmission Dynamics, Drug Resistance, and Subtyping Tool Evaluation.

Viruses - 12 May 2026

Mortier Virginie, Debaisieux Laurent, De Geyter Deborah, Delforge Marie-Luce, Depypere Melissa, Dessilly Géraldine, Kabamba-Mukadi Benoît, El Moussaoui Khalid, Mzougui Samy, Serrien Ben, Stoffels Karolien, Van Beckhoven Dominique, Van Cutsem Ellen, Van den Bossche Dorien, Van den Wijngaert Sigi, Vanroye Fien, Padalko Elizaveta, Verhofstede Chris, Van Laethem Kristel

Abstract excerpt

The international spread of HIV-1 sub-subtype A6 raises concerns due to its association with contraindications for long-acting injectable formulations of cabotegravir (LA-CAB) and rilpivirine (LA-RPV). This study investigated its increasing proportion in Belgium, assessing transmission dynamics and potential migration links. Additionally, genotypic drug resistance in the Belgian HIV-1 sub-subtype A6 population...

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PMID: 42198757
DOI: 10.3390/v18050554
PMCID: PMC13211556

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