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Evaluation of HIV-1 transmitted drug-resistance among subtypes circulating from 2022 to 2024 in Italy: a refined analysis through next-generation sequencing.

The Journal of antimicrobial chemotherapy - 4 Mar 2026

Armenia Daniele, Alteri Claudia, Micheli Valeria, Allice Tiziano, Bonura Celestino, Bruzzone Bianca, Bon Isabella, Corsini Romina, Zerbini Alessandro, Morelli Loriana, Cerutti Francesco, Giammanco Giovanni, Randazzo Nadia, Bertoldi Alessia, Novazzi Federica, Ibba Gabriele, Bertoli Ada, Bezenchek Antonia, Ceccherini-Silberstein Francesca, Zazzi Maurizio, Santoro Maria Mercedes

Abstract excerpt

BACKGROUND: Monitoring HIV-1 subtype circulation and transmitted drug resistance (TDR) remains a key priority, particularly since the rollout of high-sensitivity next-generation sequencing (NGS). METHODS: Routine plasma HIV-1 RNA NGS genotyping data were collected from newly diagnosed individuals in Italy over 2022-24. HIV-1 TDR and genotypic susceptibility were evaluated through HIVdb with NGS set at 10% and...

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Anti-HIV Agents
Drug Resistance, Viral
High-Throughput Nucleotide Sequencing
HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41826804
DOI: 10.1093/jac/dkag084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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