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CATVariant: a web server for integrated protein variant interpretation across sequence, structure, population, and clinical evidence.

Nucleic acids research - 11 Jul 2026

Ngo Khoa, Amini Hajar, Vorobyov Igor, Clancy Colleen E

Abstract excerpt

Efficient interpretation of the structural, functional, and clinical impact of protein variants remains a longstanding challenge. This difficulty arises because evidence needed to interpret variant effects is distributed across sequence, structure, population, clinical, experimental, and literature resources. CATVariant (https://catvariant.khoa.ngo) is an open-access web server that addresses this gap by...

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PMID: 42186440
DOI: 10.1093/nar/gkag518
PMCID: PMC13355051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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