Article
CmBt and CmBr synergistically regulate cucurbitacin B biosynthesis in melon.
Plant physiology - 2 Jun 2026
Wang Shiqi, Zhao Xue, Wang Xinru, Wang Mingyan, Wang Chuangjiang, Liu Mengke, Zhu Yaxuan, Liu Tingting, Wang Yichen, Chen Xinxiu, Xu Yuanchao, Cheng Fei, Che Xinhui, Liu Xiaofeng, Lv Bingsheng, Chai Sen, Xu Kuipeng, Zhang Zhonghua, Zhang Huimin
Abstract excerpt
Cucurbitacin B (CuB) is the primary compound responsible for bitterness in melon (Cucumis melo L.) and negatively affects fruit quality and consumer acceptance. Although CuB biosynthesis is regulated by multiple transcription factors, the regulatory mechanisms underlying CuB biosynthesis across different tissues remain unclear. Here, we generated 2 independent knockout lines (Cmbt-18 and Cmbt-19) of the basic...
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