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The Role of Two Glycoalkaloid Metabolism Genes in α-Tomatine Biosynthesis and Basal Defence in Tomato.

Molecular plant pathology - 1 Jun 2026

You Yaohua, Balaji Aishwarya, Herrera Valderrama Andrea Lorena, Denarié Marie-Emma, Suraj H M, Ramirez Gaona Miguel, Hanika Katharina, Verstappen Francel, Kappers Iris F, van Kan Jan A L

Abstract excerpt

Steroidal glycoalkaloids and saponins are plant cholesterol-based steroid metabolites with antimicrobial activities and potential pharmacological value. The saponin uttroside B from black nightshade (Solanum nigrum) plays an important role in defence against herbivorous insects and exhibits anti-hepatocellular carcinoma activity. The tomato (Solanum lycopersicum) glycoalkaloid α-tomatine has been studied because...

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PMID: 42216500
DOI: 10.1111/mpp.70275
PMCID: PMC13239889

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