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Article

Unlocking translational control of specialized metabolism in plants through 5'UTR structure.

Science advances - 22 May 2026

Lin Makou, Shin Doosan, Hao Jie, Jan Masood, Park Minkyu, Perez Veronica, Breuer Benjamin, Wang Ying, Kim Jeongim

Abstract excerpt

Plant-specialized metabolites are essential for plant fitness and human health, with their biosynthesis pathways tightly regulated at multiple levels. However, the translational regulation of their biosynthesis remains poorly understood. Here, we reveal a 5' untranslated region (5'UTR)-mediated translational mechanism that controls glucosinolate production in Arabidopsis. A forward genetic screen exploring the...

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Identifiers

PMID: 42172341
DOI: 10.1126/sciadv.aeb6806
PMCID: PMC13196742

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