Article
Mutations in eIF5B Confer Thermosensitive and Pleiotropic Phenotypes via Translation Defects in Arabidopsis thaliana.
The Plant cell - 1 Aug 2017
Zhang Liyuan, Liu Xinye, Gaikwad Kishor, Kou Xiaoxia, Wang Fei, Tian Xuejun, Xin Mingming, Ni Zhongfu, Sun Qixin, Peng Huiru, Vierling Elizabeth
Abstract excerpt
The conserved eukaryotic translation initiation factor 5B, eIF5B, is a GTPase that acts late in translation initiation. We found that an Arabidopsis thaliana mutant sensitive to hot temperatures 3 (hot3-1), which behaves as the wild type in the absence of stress but is unable to acclimate to high temperature, carries a missense mutation in the eIF5B1 gene (At1g76810), producing a temperature sensitive protein. A...
Topics
- Alleles
- Arabidopsis
- Arabidopsis Proteins
- DNA, Bacterial
- Electron Transport
- Eukaryotic Initiation Factors
- Gene Expression Regulation, Plant
- Genetic Complementation Test
- Genetic Pleiotropy
- Heat-Shock Response