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Article

[Research progress on the association of cardiac ion channel gene variants with hypertrophic cardiomyopathy and related arrhythmias].

Zhonghua xin xue guan bing za zhi - 24 May 2026

Ma X Y, Zhao J, Wang B, Liu L W

Abstract excerpt

肥厚型心肌病（HCM）是一类以心肌肥厚为核心特征的遗传性心血管疾病，其发病主要由肌小节蛋白基因变异导致。近年来诸多研究显示，心脏离子通道基因变异可能在HCM的发生、发展中发挥重要作用，且该类离子通道基因变异常与心律失常合并出现。该文对HCM相关离子通道的生理功能，以及心脏离子通道基因变异引发HCM及合并心律失常的潜在致病机制与药物治疗进展作一综述，以期为HCM的临床管理及药物干预提供新思路。.

Read the complete abstract on PubMed

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Share to Arrhythmias, Cardiac
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Source

Identifiers

PMID: 42161633
DOI: 10.3760/cma.j.cn112148-20260309-00148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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