[Research progress on the genetic mechanisms of dilated cardiomyopathy in children].

Abstract excerpt

扩张型心肌病是儿童最常见的心肌病类型，婴儿期高发，以左心室扩张和收缩功能障碍为特征。该病具有显著遗传异质性，涉及50多个致病基因，30%~40%的病例可明确单基因病因，涉及肌节结构、钙调控等多种分子机制，导致心肌功能损伤和心脏重塑。本文综述儿童扩张型心肌病的遗传病因与分子机制，为探讨其精准治疗策略提供参考。.

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