Article
Intestinal obstruction impairs feeding and promotes sleep in Drosophila melanogaster.
Science advances - 22 May 2026
Reinger Cindy, Blackie Laura, Medeiros Alexandra M, Gillet Hugo, Kring Carolin, Gaspar Pedro, Hadjieconomou Dafni, Sickmann Michèle, Affolter Markus, Miguel-Aliaga Irene, Müller Martin, Kempf Anissa
Abstract excerpt
At the onset of life, feeding must be initiated while developmental waste products-the meconium-need to be eliminated. Although these two fundamental physiological processes are interconnected, their mechanistic coupling remains poorly understood. Using Drosophila as a model system, we investigated the coordination of these processes. We show that meconium excretion starts shortly after eclosion and that feeding...
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