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Article

Mixed Phenotype Acute Leukemia with B/T Lineage and BCR-ABL1 Rearrangement: a Case Report and Literature Review.

Clinical laboratory - 1 May 2026

Mamad Hassane, Siyar Hamza, Zirar Jalila, Regragui Ismail, Benkirane Souad, Masrar Azlarab

Abstract excerpt

BACKGROUND: We report a case of B/T mixed phenotype acute leukemia (MPAL) with BCR-ABL1 rearrangement in a 35-year-old male presenting with hemorrhage, infection, and hemodynamic instability. METHODS: Laboratory findings showed bicytopenia (hemoglobin 79 g/L, platelets 17 x 10⁹/L), leukocytosis (7.7 x 10⁹/L). Peripheral blood and bone marrow smears showed 22% and 66% myeloperoxidase-negative blasts, respectively....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42159131
DOI: 10.7754/Clin.Lab.2025.250715

Genes

ABL1
BCR
CD19
CD2
CD5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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