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Article

Comparative performance of L1- and E6/E7-targeted HPV genotyping assays based on a unified MeltArray platform.

Microbiology spectrum - 7 Jul 2026

Liu Yuli, Qu Huihui, Zhang Feng, Gan Shuyang, Lai Yongqing, Zhang Xiaoxing, Zhong Meiying, Yang Xinyi, Xu Ye, Liao Yiqun, Li Qingge

Abstract excerpt

Human papillomavirus (HPV) molecular testing is central to cervical cancer screening. Commercial assays commonly target either the L1 gene or the E6/E7 oncogenes, yet comparative performance data under standardized conditions remain limited. We developed two HPV genotyping assays targeting L1 and E6/E7 regions, respectively, using the same MeltArray platform to minimize technical variability. Both assays detect...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42148574
DOI: 10.1128/spectrum.00206-26
PMCID: PMC13340185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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