Article
Development of a Multiplex PCR Test with Automated Genotyping Targeting E7 for Detection of Six High-Risk Human Papillomaviruses.
PloS one - 1 Jan 2015
Paes Eliana Ferreira, de Assis Angela Maria, Teixeira Cirbia S Campos, Aoki Francisco Hideo, Teixeira Julio Cesar
Abstract excerpt
Cervical cancer is caused by high-risk human papillomaviruses (HPV) and viral detection tests aid in the diagnosis of precursor lesions. In the present study, a molecular test for detection of high-risk HPV DNA, called E7-HPV, was standardized and assessed in samples from women with pre-cancerous lesions. The development of the E7-HPV test for detection and genotyping of six high-risk HPV (types 16, 18, 31, 33,...
Topics
- Alphapapillomavirus
- Cervix Uteri
- DNA, Viral
- Female
- Genotype
- Genotyping Techniques
- Humans
- Multiplex Polymerase Chain Reaction
- Papillomaviridae
- Papillomavirus Infections