Article
Establishment and Application of a Method for High-Risk Human Papillomavirus Genotyping in Cervical Cancer Tissue.
Clinical laboratory - 1 Jan 2016
Zou Ruanmin, Xie Wangkai, Wang Huijing, Wang Jian, Xiao Lanlan, Ji Shuhui, Chen Xiangmin, Zhang Lifang, Xue Xiangyang, Chen Jun
Abstract excerpt
BACKGROUND: Persistent high-risk HPV infection is a major cause of cervical cancer and E6/E7 genes and the Li gene in the HPV genome are key targets to detect high-risk HPV. This study aims to explore the relationship between cervical lesions and E6/7 by establishing a polymerase chain reaction (PCR) to detect multiplex genes based on HPV EE7 genes. It is hoped that such methods will provide a more reliable...
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