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Article

The genetic architecture of autistic traits and negative symptoms in non-affective first-episode psychosis: an exploratory longitudinal study.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Oct 2026

Mezquida G, Perez-Ramos A, Guasch-Capella N, Forte M F, Parellada M, Amoretti S, Serra-Navarro M, Galvañ J, Cuesta M J, Mané A, la Serna E De, Mitjans M, Bioque M, García-Rizo C, Segura A G, Group Acronym PEPs

Abstract excerpt

Autistic traits and negative symptoms (NS) frequently co-occur in schizophrenia spectrum disorders (SSD), even in early stages such as first-episode psychosis (FEP), complicating both diagnosis and prognosis, as these dimensions strongly influence functional outcomes and may share etiological mechanisms. This study aims to explore the genetic architecture underlying autistic and NS dimensions, to support early...

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Identifiers

PMID: 42143913
DOI: 10.1016/j.euroneuro.2026.112859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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