Typical and atypical clinical profiles in syphilis patients: will genotyping of syphilis agents and patients help to explain symptom differences?

Abstract excerpt

INTRODUCTION: Syphilis, caused by Treponema pallidum subsp. pallidum, is a chronic sexually transmitted infection resulting in a broad spectrum of clinical manifestations showing a rising incidence at the global level. A high proportion of syphilis patients have atypical manifestations that may complicate clinical recognition and lead to diagnostic uncertainty and delays in treatment, thereby increasing the risk...

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