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Article

Ghrelin Inhibits Post-Operative Adhesions via Blockage of the TGF-β Signaling Pathway.

PloS one - 1 Jan 2016

Bianchi Enrica, Boekelheide Kim, Sigman Mark, Lamb Dolores J, Hall Susan J, Hwang Kathleen

Abstract excerpt

Post-operative adhesions are a critical problem in pelvic and abdominal surgery despite a multitude of studies dedicated to finding modalities to prevent their occurrence. Ghrelin administration promotes an anti-fibrotic response in a surgical mouse model of adhesion-induction, but the mechanisms mediating this effect have not been established. In the current study, the molecular mechanisms that underlie the...

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Identifiers

PMID: 27082244
DOI: 10.1371/journal.pone.0153968
PMCID: PMC4833425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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