Phenotypic clustering analysis of patients rejected for mitral valve interventions: implications for future transcatheter technologies.

doi:10.1093/ehjci/jeaf141

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Article

Phenotypic clustering analysis of patients rejected for mitral valve interventions: implications for future transcatheter technologies.

European heart journal. Cardiovascular Imaging - 31 Jul 2025

Ludwig Sebastian, Coisne Augustin, Hamzi Kenza, Ben Ali Walid, Scotti Andrea, Koell Benedikt, Duncan Alison, Makkar Raj, Akodad Mariama, Bleiziffer Sabine, Nickenig Georg, Kaneko Tsuyoshi, Ruge Hendrik, Adam Matti, Sondergaard Lars, Dahle Gry, Taramasso Maurizio, Walther Thomas, Kempfert Joerg, Obadia Jean-François, Chehab Omar, Tang Gilbert H L, Goel Sachin, Fam Neil, Denti Paolo, Praz Fabien, von Bardeleben Ralph Stephan, Hausleiter Jörg, Latib Azeem, Conradi Lenard, Modine Thomas, Pezel Théo, Granada Juan F

Abstract excerpt

AIMS: Although several treatment options are available for patients with severe mitral regurgitation (MR), a significant proportion of patients remain ineligible for any mitral valve (MV) intervention. We aimed to analyse the phenotypic characteristics of surgical high-risk patients ineligible for MV interventions using an unsupervised phenotypic clustering approach. METHODS AND RESULTS: Between 2014 and 2022,...

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PMID: 40329826
DOI: 10.1093/ehjci/jeaf141

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