Article
Limited clinical utility of mutation-based circulating tumor DNA detection in pseudomyxoma peritonei.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Jul 2026
Torgunrud Annette, Davidson Ben, Nilsen Thale Andrea, Nitschke Marcussen Ina Katrine, Dagenborg Vegar J, Lund-Andersen Christin, Flatmark Kjersti
Abstract excerpt
Pseudomyxoma peritonei (PMP) is a rare abdominal cancer where curative treatment involves cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Postoperative surveillance relies on radiological imaging and blood tumor markers, which lack sensitivity and specificity. Circulating tumor DNA (ctDNA) analysis could offer a non-invasive alternative, but evidence in PMP is limited. Plasma samples from 95...
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