Article
Significant decreased CXCR3+ phenotype Tfh1 cells in three Good's syndrome patients.
Frontiers in immunology - 1 Jan 2026
Chen Yanxia, Zhang Junwu, Ni Jinyao, He Jing, Liu Jinlin
Abstract excerpt
Background: Good's syndrome (GS) is a rare acquired immunodeficiency defined by the co-occurrence of thymoma and hypogammaglobulinemia. Follicular helper T (Tfh) cells, a specialized CD4+ T cell subset, play a critical role in supporting B-cell antibody production. The status and characteristics of Tfh cells in GS, however, remain largely unexplored. Methods: This study utilized flow cytometry to analyze...
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