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Integrating epidemiology with genomic tracing to uncover concealed transmission networks in a brucellosis outbreak, Shandong, China.

Frontiers in cellular and infection microbiology - 1 Jan 2026

Huangfu Chanjuan, Wang Min, Fan Junjie, Ma Xiujun, Zhang Haizong, Yuan Jing, Han Kuo, Liu Ti, Ding ShuJun, Kou Zengqiang, Li Yan

Abstract excerpt

Background: This study integrated epidemiological investigation with whole-genome sequencing to elucidate the transmission chain and pathogen characteristics of a 2023 brucellosis outbreak in Shandong Province, providing evidence for targeted prevention and control. Methods: Transmission chains were reconstructed through field epidemiological investigations, active case finding, and retrospective data review....

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PMID: 42093768
DOI: 10.3389/fcimb.2026.1794629
PMCID: PMC13138912

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