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Multiple Brucella melitensis lineages are driving the human brucellosis epidemic in Shaanxi Province, China: evidence from whole genome sequencing-based analysis.

Frontiers in cellular and infection microbiology - 1 Jan 2024

An Cuihong, Nie Shoumin, Luo Boyan, Zhou Dijia, Wang Wenjing, Sun Yangxin, Fan Suoping, Liu Dongli, Li Zhenjun, Liu Zhiguo, Chang Wenhui

Abstract excerpt

Introduction: Human brucellosis is a severe public concern in Shaanxi Province, China, and investigating the epidemiological relationship and transmission pattern of B. melitensis is necessary to devise control strategies. Methods: In this study, a conventional bio-typing approach and whole genome sequencing of single-nucleotide polymorphisms (SNPs) were employed to identify 189 strains. Results: Based on the...

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PMID: 39539947
DOI: 10.3389/fcimb.2024.1452143
PMCID: PMC11557520

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