Article
Performance Comparison of Computational Methods for the Prediction of the Function and Pathogenicity of Non-coding Variants.
Genomics, proteomics & bioinformatics - 1 Jun 2023
Wang Zheng, Zhao Guihu, Li Bin, Fang Zhenghuan, Chen Qian, Wang Xiaomeng, Luo Tengfei, Wang Yijing, Zhou Qiao, Li Kuokuo, Xia Lu, Zhang Yi, Zhou Xun, Pan Hongxu, Zhao Yuwen, Wang Yige, Wang Lin, Guo Jifeng, Tang Beisha, Xia Kun, Li Jinchen
Abstract excerpt
Non-coding variants in the human genome significantly influence human traits and complex diseases via their regulation and modification effects. Hence, an increasing number of computational methods are developed to predict the effects of variants in human non-coding sequences. However, it is difficult for inexperienced users to select appropriate computational methods from dozens of available methods. To solve...
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