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Article

EWSR1-rearranged renal neoplasia: Clinicopathologic and molecular characterization of 39 cases from a single institution.

Human pathology - 1 Aug 2026

Colef Robert G, Pujari Ganesh P, Sill Daniel R, Pitel Beth A, Zhang Pingchuan, Tekin Burak, Lucas Peter C, Whaley Rumeal D, Herrera Hernandez Loren, Jimenez Rafael E, Erickson Lori A, Cheville John C, Kipp Benjamin R, Halling Kevin C, Greipp Patricia T, Gupta Sounak

Abstract excerpt

We report the clinicopathologic features of EWSR1-rearranged renal neoplasia from our institution. A retrospective cohort of 39 EWSR1-rearranged renal tumors was identified using fluorescence in situ hybridization (FISH) and RNA-based next generation sequencing (NGS). A final diagnosis of Ewing sarcoma (EWS) was established in 34 of 39 cases (87%), with the remaining cases diagnosed as desmoplastic small round...

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Topics

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Share to Carcinoma, Renal Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to High-Throughput Nucleotide Sequencing

Share to In Situ Hybridization, Fluorescence

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Source

Identifiers

PMID: 42067069
DOI: 10.1016/j.humpath.2026.106135

Genes

EWSR1
ERG
FLI1
CD99
MUC4
PATZ1
WT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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