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Article

EWSR1: the promiscuous king of mesenchymal neoplasia.

Journal of clinical pathology - 20 Oct 2024

Towery Emily Anne, Papke David James

Abstract excerpt

EWSR1 is the most commonly rearranged gene in mesenchymal neoplasia, and its myriad chimeric oncoproteins drive widely disparate neoplasms. Here, we survey selected EWSR1 rearrangements, including well-described EWSR1 fusions with CREB family members, ATF1 and CREB1, as well as fusions in emerging entities such as mesenchymal neoplasms with EWSR1::PATZ1 and EWSR1::NFATC2 fusions. We also discuss recent data...

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Share to Gene Rearrangement
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39209444
DOI: 10.1136/jcp-2023-208867

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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