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Article

Non-HLA antibodies worsen the histological phenotype and prognosis of antibody mediated rejection in kidney allografts.

Kidney international - 1 Oct 2026

Lebraud Emilie, Aubert Olivier, Aouni Laïla, Garcia Virginia, Morin Lise, Eloudzeri Maëva, Lamarthée Baptiste, Zuber Julien, Ramaugé Parra Corentin, Try Mélanie, Coemans Maarten, Kuypers Dirk, Wellekens Karolien, Debyser Tim, Lehnert Priyanka Koshy, Abderrahmane Adel, Taupin Jean-Luc, Jager Chloé, Holleville Quentin, Normand Corinne, Bienaimé Frank, Garcelon Nicolas, Terzi Fabiola, Naesens Maarten, Rabant Marion, Anglicheau Dany

Abstract excerpt

INTRODUCTION: Antibody-mediated rejection (AMR) remains a leading cause of kidney allograft failure, with both HLA and non-HLA antibodies implicated in its pathogenesis. The contribution of non-HLA antibodies (non-HLA Abs) to microvascular inflammation (MVI) and graft outcome, particularly in cases lacking donor-specific anti-HLA antibodies (HLA-DSAs), remains incompletely understood. METHODS: We analyzed 571...

Read the complete abstract on PubMed

Topics

Humans
Kidney Transplantation
Graft Rejection
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

Middle Aged

Allografts

HLA Antigens

Adult

Biopsy

Kidney

Prognosis

Isoantibodies

Graft Survival

Phenotype

Case-Control Studies

Retrospective Studies

Risk Factors

Source

Identifiers

PMID: 42498055
DOI: 10.1016/j.kint.2026.06.031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

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