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Article

Circulating erythropoietin concentration associates with thromboembolism in sickle cell disease.

British journal of haematology - 1 Jul 2026

Zhang Xu, Shah Binal N, Han Jin, Nouraie Mehdi, Zhang Yingze, Machado Roberto F, Gladwin Mark T, Saraf Santosh L, Gordeuk Victor R

Abstract excerpt

Elevated erythropoietin (EPO) concentration associates with thrombotic risk in hypoxic conditions, hereditary erythrocytosis and treatment of anaemia with recombinant EPO. We evaluated sickle cell disease (SCD) patients from the University of Illinois at Chicago (UIC) and the Treatment of Pulmonary Hypertension and SCD with Sildenafil Therapy (Walk-PHaSST) study and found that higher serum EPO concentration...

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Topics

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Share to Adolescent
Share to Anemia, Sickle Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Share to Receptors, Erythropoietin

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Source

Open in PubMed Open full text

Identifiers

PMID: 42052798
DOI: 10.1111/bjh.70517
PMCID: PMC13266539

Genes

EPO
SCD
EPOR
BCL11A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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