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Article

Association of functional SNP-1562C>T in MMP9 promoter with proliferative diabetic retinopathy in north Indian type 2 diabetes mellitus patients.

Journal of diabetes and its complications - 1 Dec 2017

Singh Kanhaiya, Goyal Prabhjot, Singh Manju, Deshmukh Sujit, Upadhyay Divyesh, Kant Sri, Agrawal Neeraj K, Gupta Sanjeev K, Singh Kiran

Abstract excerpt

OBJECTIVE: Retinal angiogenesis is a hallmark of diabetic retinopathy. Matrix Metalloproteinases (MMPs) are involved in degradation of extracellular matrix (ECM). Functional SNP-1562C>T in the promoter of the MMP-9 gene results increase in transcriptional activity. The present work was designed to evaluate the contribution of functional SNP-1562C>T of MMP-9 gene to the risk of proliferative diabetic retinopathy...

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Topics

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Share to Diabetes Mellitus, Type 2
Share to Diabetic Retinopathy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Matrix Metalloproteinase 9

Share to Neovascularization, Pathologic

Share to Promoter Regions, Genetic

Share to Severity of Illness Index

Source

Identifiers

PMID: 28964682
DOI: 10.1016/j.jdiacomp.2017.08.010

Genes

MMP9

Provenance

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