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Article

Atypical catabolite repression of Geobacillus kaustophilus iol operons in the presence of ribose.

Microbiology (Reading, England) - 1 Apr 2026

Yoshida Ken-Ichi, Fukui Kaho, Osawa Takuma, Tsuji Moeka, Kado-Matsushita Miyuki, Asahi Nao, Ishikawa Shu, Shiwa Yuh, Yoshikawa Hirofumi

Abstract excerpt

Geobacillus kaustophilus HTA426 is a thermophilic Gram-positive bacterium that encodes the myo-inositol-inducible iol operons, the products of which form the myo-inositol catabolic pathway. Strain PS8 is a mutant of HTA426 that is defective in myo-inositol catabolism due to constitutive repression of the iol operons. Several spontaneous suppressor mutants of PS8, which restored growth on myo-inositol, were...

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Identifiers

PMID: 42048241
DOI: 10.1099/mic.0.001702
PMCID: PMC13130090

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