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Article

MiR-551b-5p deficiency associates with malignant phenotypes in gastric cancer: potential mediation by TRAF6.

BMC gastroenterology - 27 Apr 2026

Wang Luyao, Ni Chunhua, Xia Peichen, Liu Ying, Zhuang Tianchi, Xu Ting, Wang Danyang, Yu Hongkai, Yang Yingqi, Jiang Xiaomeng

Abstract excerpt

The inflammatory tumor microenvironment (i-TME) significantly impacts the prognosis of gastric cancer (GC). Cytokines such as IL-6 may contribute to adverse phenotypes in GC; however, their regulatory mechanisms remain unclear. The role of miR-551b-5p in other cancers suggests it can target inflammation-related genes to regulate the i-TME and influence tumor prognosis. The present study aimed to investigate...

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Share to Cell Line, Tumor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42045830
DOI: 10.1186/s12876-026-04805-6
PMCID: PMC13261840

Genes

GC
TRAF6
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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