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Article

Identifying immune cells-related phenotype to predict immunotherapy and clinical outcome in gastric cancer.

Frontiers in immunology - 1 Jan 2022

Jiang Sutian, Ding Xuzhong, Wu Qianqian, Cheng Tong, Xu Manyu, Huang Jianfei

Abstract excerpt

Background: The tumor microenvironment is mainly composed of tumor-infiltrating immune cells (TIICs), fibroblast, extracellular matrix, and secreted factors. TIICs are often associated with sensitivity to immunotherapy and the prognosis of multiple cancers, yet the predictive role of individual cells on tumor prognosis is limited. Methods: Based on single-sample gene set enrichment analysis, we combined three...

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Immunologic Factors
Immunotherapy
Phenotype
Stomach Neoplasms
Tumor Microenvironment

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PMID: 36032097
DOI: 10.3389/fimmu.2022.980986
PMCID: PMC9402937

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