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Article

Instability and Subpopulation Dynamics of Azole Trailing Phenotypes in Clinical Candida tropicalis Isolates.

Mycopathologia - 27 Apr 2026

Reddy Snigdha, Paul Saikat, Rudramurthy Shivaprakash M, Kaur Harsimran, Ghosh Anup K

Abstract excerpt

Azole antifungal "trailing growth" in Candida spp., a tolerance phenotype distinct from resistance, complicates interpretation of in vitro susceptibility and may contribute to persistent candidemia, especially in resource-limited settings. This study investigated the stability, characteristics, and mechanisms of azole trailing, primarily in the emerging pathogen Candida tropicalis. From 847 clinical C. tropicalis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42043648
DOI: 10.1007/s11046-026-01074-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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