Article
SNP-Based Identification of Mycobacterium tuberculosis Strains using TaqMan PCR.
Bulletin of experimental biology and medicine - 1 Feb 2026
Zhdanova S N, Kondratov I G, Ogarkov O B, Kulinich S V, Nesterenko A V, Oteva S Y, Kukhtina T A, Koshcheyev M E, Shugaeva S N, Sinkov V V, Rychkova L V, Kolesnikova L I
Abstract excerpt
Within the WHO framework of genomic epidemiological surveillance of tuberculosis, we have developed a panel of primers and TaqMan probes for PCR-based identification of SNPs in major epidemiological genotypes of Mycobacterium tuberculosis responsible for the spread of MDR/XDR strains in North Eurasia. Validation was performed on a dataset of 590 randomly selected strains circulating in the Krasnoyarsk Krai and...
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