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Indigenous people from Amazon show genetic signatures of pathogen-driven selection

8 Mar 2023

Abstract excerpt

Ecological conditions in the Amazon rainforests are historically favorable for the transmission of numerous tropical diseases, especially vector-borne diseases. The high diversity of pathogens likely contributes to the strong selective pressures for human survival and reproduction in this region. However, the genetic basis of human adaptation to this complex ecosystem remains unclear. This study investigates the...

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PMID: 36888716
DOI: 10.1126/sciadv.abo0234

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