Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Knockout of tusA confers cationic antimicrobial resistance via fur and omp genes in Escherichia coli.

Journal of bacteriology - 21 May 2026

Ishikawa Kazuya, Nakata Kiho, Yamada Koichiro, Uneme Mio, Furuta Kazuyuki, Kaito Chikara

Abstract excerpt

tRNA 2-thiouridine synthesizing protein A (TusA), a sulfur-carrier protein, plays a crucial role in tRNA sulfur modification. Several studies have reported that tusA deficiency affects iron-sulfur (Fe-S) homeostasis in addition to tRNA sulfur modification, resulting in pleiotropic phenotypes. In this study, we analyzed the phenotype of tusA-deficient Escherichia coli and its underlying mechanisms. Although the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Cationic Peptides
Share to Bacterial Outer Membrane Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Bacterial

Share to Escherichia coli Proteins

Share to Flagella

Share to Gene Expression Regulation, Bacterial

Share to Gene Knockout Techniques

Share to Repressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 42017776
DOI: 10.1128/jb.00103-26
PMCID: PMC13192261

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 16 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Knockout of tusA confers cationic antimicrobial resistance via fur and omp genes in Escherichia coli.PMID 42017776Read ↗

TusA Is a Versatile Protein That Links Translation Efficiency to Cell Division in Escherichia coli.Semantic proximity Read ↗

TusDCB, a sulfur transferase complex involved in tRNA modification, contributes to UPEC pathogenicitySemantic proximity Read ↗

Rethinking the Primary Functions of the “Tellurium Resistance Genes”Semantic proximity Read ↗

The sulfur carrier protein TusA has a pleiotropic role in Escherichia coli that also affects molybdenum cofactor biosynthesis.Semantic proximity Read ↗

Inactivation of thyA in Staphylococcus aureus Attenuates Virulence and Has a Strong Impact on Metabolism and Virulence Gene ExpressionSemantic proximity Read ↗

Identification of two tRNA thiolation genes required for cell growth at extremely high temperatures.Semantic proximity Read ↗

PmtA functions as a ferrous iron and cobalt efflux pump in Streptococcus suisSemantic proximity Read ↗

The Two-Component System ChtRS Contributes to Chlorhexidine Tolerance in Enterococcus faecium.Semantic proximity Read ↗

The <i>Klebsiella pneumoniae ter</i> operon enhances stress toleranceSemantic proximity Read ↗

Increased resistance against tellurite is conferred by a mutation in the promoter region of uncommon tellurite resistance gene tehB in the ter-negative Shiga toxin-producing Escherichia coli O157:H7.Semantic proximity Read ↗

A novel suicide shuttle plasmid for Streptococcus suis serotype 2 and Streptococcus equi ssp. zooepidemicus gene mutation.Semantic proximity Read ↗

The intrinsic macrolide resistome of Escherichia coliSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.