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The Two-Component System ChtRS Contributes to Chlorhexidine Tolerance in Enterococcus faecium.

Antimicrobial agents and chemotherapy - 1 May 2017

Guzmán Prieto Ana M, Wijngaarden Jessica, Braat Johanna C, Rogers Malbert R C, Majoor Eline, Brouwer Ellen C, Zhang Xinglin, Bayjanov Jumamurat R, Bonten Marc J M, Willems Rob J L, van Schaik Willem

Abstract excerpt

Enterococcus faecium is one of the primary causes of nosocomial infections. Disinfectants are commonly used to prevent infections with multidrug-resistant E. faecium in hospitals. Worryingly, E. faecium strains that exhibit tolerance to disinfectants have already been described. We aimed to identify and characterize E. faecium genes that contribute to tolerance to the disinfectant chlorhexidine (CHX). We used a...

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Identifiers

PMID: 28242664
DOI: 10.1128/AAC.02122-16
PMCID: PMC5404517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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