Mendelian Randomization Study in East Asian Populations Supports the Causal Relationship Between Blood Metabolites and COPD: Insights from Amino Acids, Phospholipids, Vitamin D, and Trace Elements.

Abstract excerpt

Background: Chronic obstructive pulmonary disease (COPD) is the most common respiratory disease among middle-aged and older adults worldwide, and its etiology remains incompletely understood. As intermediate products of biochemical reactions, blood metabolites have a debated role in the pathogenesis of COPD, with observational studies yielding conflicting results. Most existing genetic studies are based on...

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• Amino Acids
• Biomarkers
• East Asian People
• Genome-Wide Association Study
• Mendelian Randomization Analysis