Ilunocitinib-Induced Pancytopenia in an Australian Shepherd Dog with the MDR1 Mutation.

Abstract excerpt

A 5 yr old female spayed Australian shepherd dog with a prior diagnosis of atopy presented for increased pruritus despite immunotherapy. The dog had a history of seizures well controlled by levetiracetam and was genotyped as MDR1 mutant/normal. Ilunocitinib, indicated for controlling pruritus in dogs, was considered. Because the label indicates ilunocitinib can cause cytopenias, a complete blood count (CBC) was...

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