Article
A novel enterotype enriched with respiratory super-dominant pathobionts is associated with immunosuppression in pulmonary tuberculosis patients.
Journal of translational medicine - 20 Apr 2026
Yuan Tingting, Chen Jiali, Zheng Han, Pu Ji, Li Lianfeng, Lu Shan, Sun Yamin, Lin Wenchao, Yang Jing, Xu Jianguo
Abstract excerpt
BACKGROUND: Perturbations of the gut microbiota in pulmonary tuberculosis (PTB) patients, often antibiotic-induced, are frequently observed; however, the defining features of this dysbiosis and its relationship with clinical phenotypes remain insufficiently characterized. METHODS: In this cross-sectional study, we collected fecal samples from 66 PTB patients and performed 16S rRNA gene (V3-V4) sequencing....
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