Article

The impact of tuberculosis and its treatment on the lung and gut microbiota: A global systematic review, meta-analysis, and amplicon-based metagenomic meta-analysis

2025-08-27

Abstract excerpt

<h4>Background</h4> Tuberculosis (TB) remains the leading cause of bacterial disease-related deaths worldwide. Historically, the Koch’s single-causative-agent model has shaped diagnostics, treatment, and prevention. However, metagenomic studies have unveiled the presence of a lung microbiome, which is disrupted by TB and its orally administered treatment, with downstream effects on the gut microbiome. These chang...

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Literature Corpus work: 02a4635e-2595-502b-bef6-515f4daa1031
DOI: 10.1101/2025.08.25.25334361

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